Please, read all of this information to understand the the power of this therapy as it relates to your health issue and think about sharing it with someone else who would need to have this information..
Bill Marcella
You can listen to an audio presentation by a Dr. Dennis Clark about systemic enzymes Click Here
or just read on to find out more.
Systemic Enzymes Explained

As we get older our enzyme levels and activity decrease. When combined with poor diet, illness and injury, we can suffer from an enzyme deficiency, which causes our bodies and normal bodily functions to start breaking down.
Systemic enzymes are the foundation that makes all of your other vitamin supplements work properly. As a biocatalyst, enzymes help to drive multiple reactions throughout the body. We have roughly 3,000 enzymes in our bodies, and over 7,000 enzymatic reactions.
These enzymes attack fibrin and may reduce the impact of fibrin buildup associated with arthritic and inflammatory conditions, plaque build up within the arteries, scar tissue, production of C-Reactive Protein (CRP) and Fibrosis
.[See Picture Above]
- Powerful anti-inflamatory out performs aspirin,
ibuprofen, Celebrex, Vioxx and all other nsaid drugs!
- Digests scar tissue…old or new!
- Is anti-fibrosis, literally eating and digesting fibrin deposits
(Much like a layer of fiberglass webbing found on internal
organs, soft tissues and muscles).A breakthrough for those
who suffer from fibromyalgia and fibrocystic disease!
- Dissolves blood clots and cysts!
- Breaks down and digests the coating that protects
and houses viruses to render them inert and harmless!
- Immune Modelator, which restores a steady state to the body!
- Digests arterial plaque!
- Creates tremendous energy and feeling of well being!
- Digests spider veins!
Also, the following are the types of conditions that customers have reported having benefited from Serrapeptase and that studies have shown that Serrapeptase can benefit:
Chronic Fatigue Syndrome |
Thickened Blood |
Endometreosis |
High Cholesterol |
Osteoarthritis |
Circulatory Disorders |
Rheumatoid-Arthritis |
Clogged Arteries |
Pulmonary Fibrosis |
Allergies |
Wrinkles |
Chronic Sinusitis |
Joint and Muscle Inflammation |
Carpal Tunnel Syndrome |
Proteolytic enzyme (Protease):
The term "proteolytic" refers to all enzymes that digest protein. Other classes of enzymes include Amylase a digestive enzyme that breaks down carbohydrates and Lipase a digestive enzyme that breaks down fat during the digestive process. Each of these help in the digestion of food which in turn helps with absorption of those essential nutrients in the diet. In the body, proteolytic digestive enzymes are produced in the pancreas, but supplemental forms of enzymes may come from fungal or bacterial sources, extraction from the pancreas of livestock animals (trypsin/chymotrypsin) or extraction from plants (such as papain from the papaya and Bromelain from pineapples). The primary uses of proteolytic enzymes in dietary supplements are used as digestive enzymes, anti-inflammatory agents and pain relievers. There are a number of clinical trials showing the benefit of using oral proteolytic enzymes as a digestive aid. Proteolytic enzymes are also theorized to help reduce symptoms of food allergies and as a treatment for rheumatoid arthritis and other autoimmune diseases Perhaps the strongest evidence for benefits of proteolytic enzyme supplements come from numerous European studies showing various enzyme blends to be effective in accelerating recovery from exercise and injury in sportsmen as well as tissue repair in patients following surgery. In one study of footballers suffering from ankle injuries, proteolytic enzyme supplements accelerated healing and got players back on the field about 50% faster than athletes assigned to receive a placebo tablet(1). A handful of other small trials in athletes have shown enzymes can help reduce inflammation, speed healing of bruises and other tissue injuries (including fractures) and reduce overall recovery time when compared to athletes taking a placebo(2-8). In patients recovering from facial and various reconstructive surgeries, treatment with proteolytic enzymes significantly reduced swelling, bruising and stiffness compared to placebo groups (9-11). Serrapeptase
Serrapeptase:
Also known as Serratia peptidase, is a proteolytic enzyme isolated from the non-pathogenic enterobacteria Serratia E15. The enzyme is found naturally in the intestine of the silkworm, which is used by the silkworm to dissolve the cocoon and emerge as a moth. When consumed in unprotected tablets or capsules, the enzyme is destroyed by acid in the stomach. However, when enterically coated the enzyme passes through the stomach unchanged, and can be absorbed in the intestine. It has many clinical uses including: as an anti-inflammatory agent (particularly for post traumatic swelling) for Fibrocystic breast disease for Bronchitis (Serrapeptase loosens and expels mucous). Serrapeptase digests dead tissue, blood clots, cysts, and arterial plaque. The late German physician Dr. Hans Nieper, used serrapeptase to treat arterial blockage in his coronary patients. Clinical studies show that serrapeptase induces fibrinolytic, anti-inflammatory and anti-edemic (prevents swelling and fluid retention) activity in a number of tissues, and that its anti-inflammatory effects are superior to other proteolytic enzymes(12). Besides reducing inflammation, one of serrapeptase's most profound benefits is reduction of pain, due to its ability to block the release of pain-inducing amines from inflamed tissues(13) Physicians throughout Europe and Asia have recognized the anti-inflammatory and pain-blocking benefits of this naturally occurring substance and are using it in treatment as an alternative to salicylates, ibuprofen, and other NSAIDs(14).
Bromelain & Papain:
Both Bromelain and Papain are plant derived proteolytic enzymes. Bromelain, also known as bromelin, is a protein-digesting enzyme extracted from the flesh and stem of the pineapple plant, Ananas comosus. Papain, is a proteolytic enzyme isolated from the papaya plant, Carica papaya. Bromelain is most notable for its effectiveness in the reduction of inflammation and decreasing swelling, but the scope of its benefits continues to increase. As a natural anti-inflammatory enzyme, bromelain has many uses. Arthritis patients may reduce the swelling that causes joint pain by taking bromelain. Bromelain may also be helpful for the pain, numbness, tingling, aching, and loss of motor and sensory function in the fingers resulting from carpal tunnel syndrome (CTS) (15,16). Prevention of the adhesiveness of platelets to endothelial cell walls was accomplished with 0.1 mcg/ml of Bromelain(16a). Thus the benefit of bromelain occurs over a broad range of doses, and even small amounts may be beneficial to anyone at risk to thrombotic heart attack or stroke. Papain has been shown to be effective in preventing burn wound infection and helping remove dead cells(17). Papain is also used for the following: Defibrinating wounds in hospitals Preventing cornea scar deformation Used in treatments of jellyfish and insect stings To treat edemas, inflammatory processes, and in the acceleration of wound healing In low doses as an indigestion medicine Papain has been used to treat ulcers, dissolve membranes in diphtheria and reduce swelling, fever and adhesions after surgery.
Amla:
Also known as Indian gooseberry (Emblica officinalis) is the richest source of Vitamin C. It also contains tannic acid, glucose, protein, cellulose and Calcium. Amla is useful for stomach problems, it is antipyretic, hair tonic and nerve brain tonic. It's also useful in anemia, hyperacidity and in gynecological problems and epistaxis. Amla is considered to have restorative and preventive properties.
Rutin:
One of the many existing Flavonoids. Flavonoids are a class of water-soluble plant pigments. Flavonoids support health by strengthening capillaries and other connective tissue, and some function as anti-inflammatory, antihistaminic, and antiviral agents. Rutin and several other flavonoids may also protect blood vessels. Rutin was shown to stimulate wound healing in rats and augment the tensile strength of scar tissue significantly(18).
Using Systemic Enzymes as a Natural Anti-Inflammatory
Enzymes are the first line of defense against inflammation. (1,2,3). Inflammation is a reaction by the immune system to an irritation. Let's say you have an injured right knee. The immune system, sensing the irritation in the knee, creates a protein chain called a Circulating Immune Complex (CIC for short), tagged specifically for that right knee. (A scientist who found the tagging mechanism won the Nobel Prize in biology in 1999). This CIC floats down to the right knee and causes pain, redness and swelling - the classic earmarks for inflammation. This, at first, is a beneficial reaction; it warns us that a part of ourselves is hurt and needs attention. But, inflammation is self-perpetuating, it creates an irritation that in response, the body makes CIC's for!
Aspirin, Ibuprofen, Celebrex, Viox and the rest of the Non Steroidial Anti Inflammatory Drugs all work by keeping the body from making all the CIC's. This ignores the fact that some CIC's are vital to life, like those that maintain the lining of the intestines and those that keep the kidneys functioning! Not to mention the fact that they, along with acetaminophen, are highly toxic to the liver. Every year 20,000 Americans die from these over the counter drugs and another 100,000 will wind up in the hospital with liver damage, kidney damage or bleeding intestines from the side effects of these drugs. (4,5).
Systemic enzymes, on the other hand, are perfectly safe and free of dangerous side effects. They have no LD-50, or toxic dose. (6). Best of all, systemic enzymes can tell the difference between the good CIC's and the bad ones. This is due to the fact that hydrolytic enzymes are lock and key mechanisms and their "teeth" will only fit over the bad CIC's. So instead of preventing the creation of all CIC's, systemic enzymes just "eat" the bad ones and in so doing, lower inflammation everywhere. With that, pain is also lowered.
Systemic Enzymes for Anti Fibrosis
Enzymes eat scar tissue and fibrosis. (7). Fibrosis is scar tissue and most doctors learn in anatomy that it is fibrosis that eventually kills us all. Let me explain. As we age, which starts at 27, we have a diminishing of the body's output of enzymes. This is because we make a finite amount of enzymes in a lifetime and we use up a good deal of them by the time we reach our 40's (Cystic Fibrosis patients who have virtually no enzyme production to speak of, even as children usually don't make it past their 20's before they die of the restriction and shrinkage in the lungs from the formation of fibrosis or scar tissue).
So our body begins to dole out our enzymes with an eyedropper instead of with a tablespoon. Result: the repair mechanism of the body goes off balance and has nothing to reduce the over abundance of fibrin it deposits in nearly everything from simple cuts, to the inside of our internal organs and blood vessels. It is then when most women begin to develop things like fibrocystic breast disease, uterine fibroids, and endometriosis. We all grow arterial sclerotic (meaning scar tissue) plaque, and have fibrin begin to spider web its way inside of our internal organs, reducing their size and function over time. This is why as we age our wounds heal with thicker, less pliable, weaker and very visible scars.
If we replace the lost enzymes, we can control and reduce the amount of scar tissue and fibrosis our bodies have. As physicians in the US are now discovering, even old scar tissue can be "eaten away" from surgical wounds, pulmonary fibrosis, and kidney fibrosis even keloid years after their formation. Medical doctors in Europe and Asia have known this and used orally administered enzymes for such for over 40 years!
Systemic Enzymes and Blood Cleansing
The blood is not only the river of life; it is also the river through which the cells and organs dispose of their waste. Enzymes improve circulation by eating the excess fibrin that causes blood to sometimes get as thick as catsup or yogurt, creating the perfect environment for the formation of clots. All of this material is supposed to be cleaned off by the liver on "first pass" or the first time it goes through. Given the sluggish and near toxic or toxic states of everyone's liver these days, that seldom happens. So the waste remains in the blood, waiting for the liver to have enough free working space and enough enzymes to clean it. This can take days or in some people, weeks! (8).
When systemic enzymes are taken, they stand ready in the blood and take the strain off of the liver by:
- Cleaning excess fibrin from the blood and reducing the stickiness of blood cells. These two actions minimize the leading causes of stroke and heart attack: blood clots (8).
- Breaking dead material down small enough that it can immediately pass into the bowel. (8).
- Cleansing the FC receptors on the white blood cells, improving their function and availability to fight off infection. (9).
And here we come to the only warning we have to give concerning the use of Vitalzym or any other systemic enzyme - don't use the product if you are a hemophiliac or are on prescription blood thinners like coumadin, heparin and plavix. The enzymes cause the drugs to work better, so there is the possibility of thinning the blood too much.
Systemic Enzymes to help Modulate the Immune System
Enzymes are adaptogenic, seeking to restore a steady state to the body. (9). When the immune system is running low, we become susceptible to infectious disease. When it's cranked up too high, then the system creates antibodies that attack it's own tissues, as are seen in the autoimmune diseases of MS, Rheumatoid Arthritis, and Lupus. Here the Vitalzym will tone down immune function and eat away at the antibodies the immune system is making to attack its bodies own tissue.
When the immune system is run down too low, the enzymes increase immune response, producing more Natural Killer cells, and improving the efficiency of the white blood cells, all leading to improved immunity.
Systemic Enzymes for Fighting Viruses
Viruses harm us by replicating in our bodies. To do this, a virus must bond itself to the DNA in our cells through the medium of its exterior protein cell wall. Anything that disrupts that cell wall inhibits the ability of viral replication by rendering individual viruses inert. (10, 11). Systemic enzymes can tell the difference between the proteins that are supposed to be in your body and those that are foreign or not supposed to be there (again the enzyme lock and key mechanism). Vitalzym has the strongest protein eating effect of any enzyme due to its Serrapeptase content and can be of help in combating viruses.
For more information on Systemic Enzyme Therapy Click Here
Other conditions enzymes help are:
- Infections - Viruses can be made inert by enzyme action. Preventing inflammation speeds up recovery from sinusitis, bronchitis, and colds.
- Malignancies - Tumor cells are surrounded by a layer of fibrin 15 times greater than the fibrin which surrounds healthy cells. The fibrin coating enables cancer cells to escape killing by phagocytes, killer lymphocytes, and cytokines. Enzymes dissolve this coating improving survival in cancer.
- Arteriosclerosis - Excessive clotting and inflammation are routine in the developing arterial plaques. Enzyme therapy digests the fibrin and reverses the inflammation which results in decreasing the size of the artery obstructing plaques. Symptoms of angina, impaired blood flow to the brain, and poor circulation to the legs often disappear.
- Allergic Diseases - Hay fever, asthma, and urticaria (hives) are all associated with inflammation which increases the symptoms. Enzymes not only reverse this but regular use of low doses of enzymes may prevent symptoms from reappearing.
- Painful Conditions (Trauma) - Enzymes can block the release of pain producing amines from tissues that are becoming inflammed. This means that early use of large doses of enzymes in broken bones, dislocated joints, sunburn, dental extractions, injuries, and migraine headaches have the capability of preventing swelling and pain from appearing.
- Estrogen Excess Disorders - Several health problems experienced by females are related to excessive production of estrogen (fibrocystic disease of the breast, fibroids of the uterus). Enzyme therapy helps both these conditions. Endometriosis causes a profound painful inflammatory reaction that results in scarring and sterility. This scarring and pain can be prevented by early use of enzymes.
- Keloids - Some individuals develop greatly enlarged unsightly scars which can be prevented and dissolved with enzymes.
- Lung Diseases - Scarring of the delicate alveolar membranes vital to transfer of carbon dioxide for oxygen leads to pulmonary fibrosis. Sarcoidosis can produce widespread scarring in lung tissue. Both these disorders and many other lung diseases should be helped by enzyme therapy.
- Arthritic Diseases - All joint diseases manifest swelling and pain. (osteoarthritis, rheumatoid arthritis, bursitis) which enzymes can alleviate. Systemic lupus erythematosus has circulating immune complexes and scleroderma has extensive scarring both of which respond to enzymes. Fibromyalgia patients have recovered using enzymes probably because of improving blood flow in the painful areas..
- Kidney Diseases - Glomerulonephritis (Bright’s Disease) has circulating immune complexes and inflammation in the kidney which should improve with enzymes. Inflammation is a prominent feature of most kidney diseases which suggests enzymes could be beneficial.
- Arteriosclerosis - Inflammation plays a key role in causing artery plaques to appear. There is also a tendency to excessive clotting. Both these problems can be reversed by systemic enzymes permitting the existing plaques to slowly disappear with disappearance of symptoms (angina, exertional leg pain, brain dysfunction from poor blood flow).
References
1) Carroll A., R.: Clinical examination of an enzymatic anti-inflammatory agent in emergency surgery. Arztl. Praxis 24 (1972), 2307.
2) Mazzone A, et al.: Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double blind, randomized trial versus placebo. J Int Med Res. 1990; 18(5):379-88.
3) Kee W., H. Tan S, L., Lee V. Salmon Y. M.: The treatment of breast engorgement with Serrapeptase: a randomized double blind controlled trial. Singapore Med J. 1989:30(I):48-54.
4) Celebrex article. Wall Street Journal. 19 April 1999.
5) No author listed: Regular Use of Pain Relievers Can Have Dangerous Results. Kaleidoscope Interactive News, American Medical Association media briefing. July 24, 1997.
6) Enzymes - A Drug of the Future, Prof. Heinrich Wrba MD and Otto Pecher MD. Published 1993 Eco Med.
7) Kakinumu A. et al.: Regressing of fibrinolysis in scalded rats by administration of serrapeptase. Biochem. Pharmacol. 31:2861-2866, 1982.
8) Ernst E., Matrai A.: Oral Therapy with proteolytic enzymes for modifying blood rheology. Klin Wschr. 65 (1987), 994.
9) Kunze R., Ransberger K., et at: Humoral immunomodulatory capacity of proteases in immune complex decomposition and formation. First International symposium on combination therapies, Washington, DC, 1991.
10) Jager H.: Hydrolytic Enzymes in the therapy of HIV disease. Zeitschr. Allgemeinmed., 19 (1990), 160.
11) Bartsch W.: The treatment of herpes zoster using proteolytic enzymes. Der Informierte Arzt. 2 (1974), 424-429.
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